Received a call from oncology nurse & the good news is that it is NOT lymphoma in the spine. The bad news is that something is there & they have no idea what it is. To compound matters, the dr was called home last weekend to his poor dying mother & he has not seen the report. This nurse is 1 sharp gal but she is having difficulty interpreting everything in the report. She just wanted me to know that it was not lymphoma. She said they took a sample of actual bone as well as 2 tubes of something from his spine. I asked her if it was possible that it was a different kind of cancer in the spine & she said possibly. She doesn't know what to make of this report & said it is almost as though his spine is crumbling. And whatever this is, it is TOTALLY different from all of those suspicious lesions that were detected exactly 2 yrs ago. It looks as though we are headed to Iowa City but don't know when; she expects dr to be back on Mon. I guess you could say we have made a complete circle: Two yrs ago, in Sept of 07, we went to a dr for possible knee replacement. This dr discovered multiple lesions (he said too many to count) up & down the entire spine. We were sent to the oncologist who told us it appeared Mike had stage 4 cancer of the spine that had metastasized from an unknown primary source. After several wks of tests, scans, etc they could not find a primary source of cancer so they finally biopsied 1 of the lesions & it was NOT cancer. But nobody could explain these lesions. We were went to Iowa City in Dec of 07 where a team of drs thoroughly examined everything: the Crohn's, knees, & most importantly the spine . In Jan of 08 these drs concluded Mike did not have cancer although things looked very suspicious. One dr suggested the lesions could be pre-cancerous markers that develop 2 to 5 yrs before the actual cancer. Drs said they had never seen a spine age in this matter & agreed with the local drs that this looked suspicious. Basically they said not to be surprised if cancer developed in the future. They said his Crohn's was extremely severe & the best thing to do for his health at that time was to address the Crohn's as aggressively as possible & that is what we started to do. Gastro dr wanted Mike on remicade infusions every 8 wks but it took several wks to get insurance approval for this treatment. In the meantime, in Feb of 08 he landed in the hospital & nearly died from the Crohn's. Dr said another 24-36hrs & they couldn't have saved him. He has a tendency to feel really bad but not complain which is why I didn't know how sick he was. Remicade approval came while Mike was in the hospital. Nine months later, in a routine scan (remember we were watching for cancer to come), they found a 2 inch spot deep in the abdomen. They did a needle biopsy but did not get enough tissue for a diagnosis so they sent us home to wait 3 months for the next scan. In the mean time, we continued with the immune suppressing drugs which in effect was like putting fertilizer on a garden & what later turned out to be cancer really flourished. In Jan of 09, during his scan, they discovered the lymphoma. By now it had spread throughout the abdomen, up thru the chest, & around the heart. In other words, almost every where. After almost 6 months of chemo we seemed to be healing & things going pretty good except for this back pain that started in late Aug but would come & go. We mentioned it to the oncologist in Sept but he wasn't concerned as all reports looked so good. The pain came more frequently & got much worse so we went to the internist in Oct. He said it was probably just muscle spams (I didn't think so but we decided to give the new meds for this a try). Finally, the pain became unbearable & almost constant so I contacted the internist again which led us to the MRI & this biopsy. So once again, we are headed back to Iowa City. And his Crohn's has now begun to raise its ugly head again but the gastro said there is not much more to be done treatment wise because of the cancer. That just about sums up the past 2+ yrs for us. Still more questions than answers. I'll keep you informed if we EVER find out what is happening to his spine.